The state is often a battleground during presidential elections, and the Democratic result will be seen by many as a blow to Trump's chances next year.
The Republican will replace Democrat Andy Beshear as attorney general, who finished his race for governor with 5,000 more votes than incumbent Matt Bevin.
"If you lose, they will say Trump suffered the greatest defeat in the history of the world", Mr Trump had said.
His campaign's push against illegal immigration tied into Cameron's efforts to nationalize the race, using conservative social issues like abortion and portraying himself in ads as a defender of President Donald Trump's agenda.
"In a late-night tweet after results came in, Trump appeared to concede the Republican may have lost: "@MattBevin picked up at least 15 points in last days, but perhaps not enough (Fake News will blame Trump!)".
In many ways Bevin was an anomaly, but this argument misses a larger point: the election may have been about as clear cut of a rejection of Trump and Trumpism in a deeply Republican state that we have ever witnessed.
Bevin, the first Republican governor in Kentucky to preside over unified party control of the legislature, has had a controversial and bitter tenure in office, waging war against teacher pensions and picking fights with members of his own party. In 2012, according to a chart prepared by the left-of-center news outlet Daily Kos, there were no fewer than nine contests for the U.S. Senate, House, and governor in which the Libertarian nominee received more votes than the difference between the winning Democrat and losing Republican.
Beshear is now the attorney general of Kentucky and son of former Kentucky governor Steve Beshear, also a Democrat, who served from 2007-2015.
Shifting explanations from White House alarm some in GOP
He said the Kurds, longtime USA allies, are "much safer right now", and added, "They're not angels". He argued the meeting with Trump became more productive after the she left the room.
Mr Bevin, 52, has reportedly said he will not concede. "And they will build it up", he told the crowd in Lexington. They won the MS governor's race, picked up seats in the New Jersey state house, and a nationally watched race for the Texas state house is headed to a run-off, where Republicans look like they are in a good position to win. She said she forwarded the request to the State Board of Elections.
Tuesday's election could help cement Democratic rule for the next decade, because the winners will decide who controls the next redistricting process.
In Mississippi, where Republican Gov. Phil Bryant was barred from running again due to term limits, Republican Lt. -Gov. "The Democrats nominated a moderate, who's dad was a moderate, who didn't talk about impeachment or Trump, and who acts like a Republican".
A mobile billboard urges voters to cast ballots for Democrats outside Centreville High School in Clifton, Virginia, Nov. 5, 2019.
Like Bevin, Reeves campaigned as a staunch Trump supporter in a state that Trump easily won in 2016. "Also holds supermajorities in both leg chambers".
Democrats will now hold all major statewide offices in Virginia and rule the state assembly, a comprehensive consolidation of power not seen there since the 1990s.
The statewide contests Tuesday inevitably reflected local candidates and conditions.
"You look at that map last night, you look at the fact that Democrats turned Kentucky blue", he added.