While everyone is asked to continue to follow coronavirus-related social distancing mandates, the South Carolina Emergency Management Division said the severe weather is the greatest threat.
In the state of MS, tornado warnings were issued for several cities.
SEVERE WEATHER SAFETY: Take time before the storms to prepare.
"Do not let the virus prevent you from seeking shelter in a tornado", it said in a statement. It appeared to weaken as it moved northward. "PLEASE AVOID THE AREA as emergency crews do their jobs", the post read.
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Alfonzo Galvan, a journalism student, recorded video of one Monroe neighbourhood with debris in the street and several homes with significant damage. If at all possible, just stay home today and tonight.
More than 95 million people are under the warnings and the storm system is expected to move up the east coast as far north as Virginia by Monday morning.
WVLT Weather Team will be providing the latest updates.
"The images and reports of major tornado damage in the Monroe area are heartbreaking, and my prayers are with the people there".
The city said that it is scrambling to provide some 200 hotel rooms to those who became homeless due to the calamity. However, utility companies reported thousands of power outages. Severe weather watches mean conditions are favorable for the development of severe storms, it does not mean severe weather is imminent. And download the KY3 First Alert Weather App while on-the-go. The best risk for strong, long-track tornadoes will be this afternoon and evening as a warm front lifts north. Supercell storms could form and abundant wind shear will support long-lived, intense convection.